Biography

S. Jamal Mustafa received my Ph.D. in Biochemistry from Lucknow University, India in 1970. In 1971, he accepted a prestigious NIH fellowship at the University Of Virginia School Of Medicine, Charlottesville, Virginia, and stayed until 1974.He became an Assistant Professor of Pharmacology at the University of South Alabama, Mobile, Alabama (1974-1980) and was soon promoted to Associate Professor at that school in 1977. He was recruited to East Carolina University School of Medicine (1980-2005) where heremained for 25 years as a Professor of Pharmacology with appointments in the Cardiovascular Center and the Departments of Medicine and Pediatrics. He received many awards including the 1995 Helms Research Award from Sigma Xi, the First Award for Excellence in Basic Research from School of Medicine, in 1997, Lifetime Achievement Award from East Carolina. He received the Distinguished Service Award in 1996 and “Mario Toppo Distinguished Scientist Award” from Association of Scientists of Indian Origin in America in 2000 and was a recipient of the Life Time Achievement Award in Research and Creative Activities from East Carolina University in June, 2003. He have published over 190 full length manuscripts.He co-edited a book on ‘Adenosine Receptors in Health and Disease’ (with Connie Wilson) in the Handbook of Experimental Pharmacology, Volume 200, Springer- Verlag GmbH (2009). During the last many years, his lab has been involved in studies related to the regulation of vascular tone and specifically the regulation of coronary flow by adenosine receptors (AR) and its signaling using various models. Their past work was instrumental in the approval by FDA (2008) of an A2A selective AR agonist (Lexican®) for myocardial perfusion imaging. Currently, we are using A1, A2A, A2B and A3 AR and their double (A2A/A2B) KOs as well as β adrenergic receptor KOs to better understand the relationship between these receptors in the regulation of coronary flow and their signaling. Additionally, Hehave a great deal of exposure to translational aspects of my work especially in the area of cardiovascular disease and asthma.